百林科兰州层析填料全新蛋白A及羟基磷灰石B15智能车间正式落成投运，
标志着百林科在制药核心耗材"国产替代"道路上，又一次从技术突破到大规模、高质量稳定供应的关键跨越。
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China has firmly rejected and condemned a new annual report by the New Zealand Security Intelligence Service on Friday which once again fabricates and sensationalizes claims about so-called "Chinese interference" and "China threat," stressing that the report is rife with Cold War thinking and contains unfounded accusations against China.
This report is clearly linked to a series of recent negative developments in New Zealand's China-related policies, a Chinese expert told the Global Times on Friday.
Recently, New Zealand has continuously toughened its rhetoric toward China, which to some extent reflects a form of "compensatory hawkishness" aimed at demonstrating its reliability within the Five Eyes alliance, Chen Hong, director of New Zealand Studies Centre, East China Normal University, told the Global Times. "Rather than reflecting 'strategic confidence,' this trend may reveal a sense of 'identity anxiety,'" Chen said.
The New Zealand intelligence agency claimed in the report released on Thursday that China is the only nation pursuing espionage in New Zealand at scale, Radio New Zealand reported. It also claimed that such activity posed threat to New Zealand, which is the "most challenging of recent times."
Many of its unfounded accusations against China either maliciously label normal exchanges, communication and cooperation as so-called espionage or interference activities, or are simply baseless fabrications. China absolutely rejects and firmly opposes this, the Chinese Embassy in New Zealand said in a statement released on Friday.
The release of this report at this time is part of a new round of attacks, smears and vilification of China orchestrated by certain international forces. In itself, the report may well be the result of foreign interference, the embassy said.
In June, security agencies from the "Five Eyes" alliance issued a warning, claiming that Chinese spies used online job platforms to recruit people with access to sensitive information, according to a Reuters report.
For now, the annual report has further escalated its rhetoric, effectively creating a chain in which the Five Eyes' warnings and New Zealand's domestic threat assessments reinforce and echo each other, the Chinese expert said.
The Lowy Institute said in a latest article on Thursday that New Zealand had long been considered the weakest link in Five Eyes and the easiest for China to try to cow. "But New Zealand has now called out China by name in its intelligence warnings so often that officials joke it has become tougher on Beijing than Australia is," the article said.
The extent to which New Zealand's intelligence agencies have publicly singled out China has in fact gone further than Australia's, which, I think, represents a compensatory hardline posture, Chen noted.
"New Zealand wants to demonstrate that it is a very active and very tough member of the Five Eyes. In fact, we have recently seen New Zealand take a high-profile stance on issues ranging from Pacific Island countries and China's relations with South Pacific and South China Sea nations to China's missile tests and other China-related issues. All of these developments can be viewed in the context of this policy shift," the expert said.
This suggests that some forces within New Zealand's security and foreign policy establishment are consciously trying to demonstrate that New Zealand is not a weak link in the Five Eyes alliance, but rather an active participant, Chen added.
The report also reflects the fact that some people both within and outside New Zealand do not want to see China-New Zealand relations develop positively. By going to great lengths to spread rumors, they seek to drive a wedge between the peoples of the two countries, create a chilling effect among the public, including overseas Chinese, undermine bilateral mutual trust, and obstruct the development of bilateral relations, the embassy noted.
Their actions serve geopolitical purposes and the narrow, short-sighted political interests of certain forces. Their intentions are clear to anyone with insight, and their objectives will not succeed.
The embassy also noted that the essence of China-New Zealand relations is mutually beneficial cooperation and win-win outcomes. In recent years, with the joint efforts of both sides, bilateral relations have made steady progress. Bilateral trade has repeatedly reached new highs, bringing substantial income and employment opportunities to New Zealanders.
People-to-people exchanges have continued to grow, with the numbers of tourists and international students increasing steadily, promoting mutual understanding and closer ties between the peoples of the two countries. The overseas Chinese community in New Zealand has played a unique and important positive role in this regard.
Since China introduced a unilateral visa-free policy for New Zealand, many New Zealand tourists have visited China, witnessing firsthand China's development achievements and openness and inclusiveness, the embassy said.
As a result of various factors, New Zealanders' understanding of China has become more comprehensive and objective in recent years, while favorable views of China and support for China-New Zealand relations have continued to rise
The embassy also warned those forces and individuals attempting to engage in political manipulation: Do not undermine the hard-won, mutually beneficial and win-win China-New Zealand relationship for your own selfish interests, thereby harming the interests of New Zealand and its people.
Acting as pawns for anti-China forces internationally will ultimately prove counterproductive. Creating controversies in foreign relations will not solve New Zealand's problems; it will likely only make matters worse, the embassy said, urging these forces and individuals not to resort to desperate measures that will ultimately harm themselves, or lift a rock only to drop it on their own feet.
China attaches importance to its relations with New Zealand and is willing to work with the New Zealand side, on the basis of the consensus reached by the leaders of the two countries, to advance exchanges and cooperation in various fields, including political mutual trust, practical cooperation and people-to-people exchanges, and to better benefit the peoples of both countries, the embassy said.
However, the development of China-New Zealand relations does not depend on China alone. We hope the New Zealand side will work in the same direction as China, rather than the opposite. Otherwise, the New Zealand side will bear responsibility for any consequences arising from such a course of action, it noted.
。以"筑基智能制造，层析健康未来"为主题的B15填料自动化产线投运启动活动，在兰州新区政府的大力支持下成功举行。百林科管理团队与生物制药产业链的关键行业伙伴，共同见证新车间及自动化产线正式投入运行。
图1：百林科管理层（从左至右：副总裁张天勇、创始人兼董事长陈志、首席执行官张铮、副总裁王智）共同为B15填料自动化产线投运启幕全新的B15 蛋白A及羟基磷灰石车间的落成投运，在百林科独特且稳定的生产工艺上结合了全自动化控制，是百林科持续推进层析填料产业化和智能制造建设的重要一步。
二 | 作为兰州新区生物医药产业布局的一部分，百林科兰州基地经过持续建设，已逐步形成覆盖研发、生产及质量管理等环节的产业化体系。
三 | 此次新产线投运，将进一步提升基地自动化生产、规模化制造及供应保障能力，为层析填料业务持续发展提供更加坚实的制造支撑。
图2：启幕仪式在关键行业伙伴的见证及兰州新区政府的大力支持下举行B15车间正式投运，智造能力再升级B15车间主要布局蛋白A全自动偶联生产线及羟基磷灰石生产线，是百林科进一步完善层析填料自动化生产体系的重要布局。目前，百林科兰州基地已建成1条500L及3条1000L全品类层析填料自动化生产线，以及一条在建的硬胶自动化生产线。搭配一条全自动灌装线, 实现智能制造全流程贯穿，有效提升效率与批次一致性，整体自动化率达到90%。其中，琼脂糖葡聚糖层析填料年产能可达 25万升, 羟基磷灰石年产能达10吨，并配备3000余平方米甲类防爆厂房，以及GMP标准D级洁净分装区及仓储区，为层析填料规模化生产提供制造基础。百林科创始人兼董事长陈志表示，自兰州填料智能制造基地建设之初，百林科就希望将其打造成为集研发、与产业化于一体的层析填料基地。B15车间的落成投运，不仅是生产设施的进一步完善，更是百林科持续提升制造能力和供应保障能力的重要一步。"智能制造的核心并不只是提高生产效率，更重要的是建立更加稳定、可控的生产体系，为客户提供稳定的产品和供应保障。
四 | "陈志表示。未来，百林科将持续推动产品、技术与制造能力协同发展，与客户共同推动国产层析填料从产品替代走向更广泛的规模化应用。
五 |
图3：B15车间内的蛋白A全自动偶联生产线全品类布局持续完善，产业化能力进一步提升B15新产线的投入运行，也进一步完善了百林科兰州基地的层析填料产品及生产布局。目前，百林科层析填料产品已覆盖葡聚糖琼脂糖软胶、聚合物硬胶、羟基磷灰石等多个产品类别，涵盖离子交换、亲和、疏水、过滤、多模式、反向等层析原理，形成百余种细分产品。此次B15车间投运，将进一步增强蛋白A、羟基磷灰石等产品的规模化生产能力，并与基地现有自动化生产线形成协同，推动百林科层析填料从多产品布局向更加完善的全品类产业化体系发展。与此同时，兰州基地通过DCS自动化控制系统及GDS系统，对生产过程进行数字化管理与安全控制，实现关键工艺参数的实时监测与自动控制，持续提升生产流程的标准化、数字化和自动化水平。2024年，兰州基地还获评甘肃省"数字化车间"。
图4：百林科兰州层析填料智造基地屡获“数字化车间”等殊荣以智能制造支撑国产层析填料发展随着生物医药产业持续发展，层析填料作为生物制药下游纯化环节的重要材料，其产品性能、质量稳定性和供应能力受到越来越多关注。对于国产层析填料而言，从产品研发走向规模化应用，不仅需要持续突破核心技术，也需要稳定、可靠的产业化制造能力。
六 | B15车间的正式投运，正是百林科围绕这一目标持续投入的重要成果。未来，百林科将持续推进核心技术研发、产品创新与智能制造能力建设，不断完善层析填料产品与产业化布局，以更加稳定、高效的制造能力，为生物制药客户提供高品质、高可靠性的层析填料及生物工艺解决方案。筑基智能制造，层析健康未来。赋能生物技术，通达无限可能。
七 |
